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Rev Clin Periodoncia Implantol Rehabil Oral. 2009;2:73-77
TRABAJO DE INVESTIGACIÓN [PDF]

Presencia de Aggregatibacter actinomycetemcomitans en Familias de Probandos con Periodontitis Agresiva

Presence of Aggregatibacter actinomycetemcomitans in Probandos Families with Aggressive Periodontitis

Contreras MJ1, Pango A2, León R3, Hidrobo R4

1Cirujano-Dentista, Universidad de Chile, alumna especialidad en Periodoncia, Universidad de Chile. Chile.
2Cirujano-Dentista, Universidad de Antofagasta, alumna especialidad en Periodoncia, Universidad de Chile. Chile.
3Biólogo, Doctor en Microbiología, Facultad de Ciencias Universidad de Chile. Departamento de Ciencias Físicas y Químicas, Laboratorio Dentaid S.A. Chile.
4Cirujano-Dentista, Universidad de Valparaíso, Especialista en Periodoncia, Universidad de Münster, Alemania. Unidad de Odontología Centro Médico San Joaquín, Universidad Católica de Chile. Chile.

Resumen

Propósito
Determinar la presencia de Aggregatibacter actinomycetemcomitans (Aa) en sujetos con diagnóstico de periodontitis agresiva (PAg) y en los individuos pertenecientes a su núcleo familiar.

Método
Se tomaron muestras microbiológicas subgingivales a 30 pacientes con P. Agresiva, 21 tenían periodontitis agresiva generalizada (PAgG) y 9 con periodontitis agresiva localizada (PAgL), para determinar la presencia de Aa. Las muestras fueron cultivadas en medios selectivos (Dentaid - 1) y Aa fue identificado por la morfología de sus colonias y por test de la catalasa. A los familiares más cercanos (30 familiares) de los probandos, también se les realizaron test microbiológicos.

Resultados
El 70% de los sujetos diagnosticados con PAg presentaban Aa. El promedio de edad de los sujetos positivos para el microorganismo fue de 30,9+7,73 años, de ellos el 33,3% presentaban PAgL. En 14 de los 21 probandos positivos para Aa se determinó la presencia de Aa, en al menos un miembro del grupo familiar. Se examinaron 30 individuos pertenecientes al núcleo familiar y el 43,3% eran positivos para Aa.

Conclusiones
Un poco más de 2/3 de los sujetos diagnosticados con PAg eran portadores de Aa y menos de la mitad de los familiares de los probandos examinados eran positivos para este microorganismo.

Palabras clave: Periodontitis agresiva, Aggregatibacter actinomycetemcomitans, transmisión intrafamiliar de A. actinomycetemcomitans.

Abstract

Aim
Determine the presence of Aggregatibacter actinomycetemcomitans (Aa) in subjects with aggressive periodontitis (AgP) and individuals as part of their family group.

Method
Subgingival plaque samples were collected from 30 aggressive, 9 localized and 21 generalized periodontitis patients, to determinate the presence of Aa. The samples were cultured on selective media (Dentaid - 1) and Aa was identified by its colony morphology and catalase test. The closest relatives (30 families) of probandos, were also conducted microbiological tests.

Results
70% of subjects were diagnosed with AgP harbored Aa. The average age of subjects positive for the pathogen was 30.9 +7.73 years, of which 33.3% had localized aggressive periodontitis. In 14 of 21 probandos found positive for Aa of at least one member of the family group. We examined 30 individuals belonging to the family and 43.3% were positive for Aa.

Conclusions
More than half of the subjects with AgP harbored Aa and less than half of the families of probandos examined were positive for this pathogen.

Key words: Agressive periodontitis, Aggregatibacter actinomycetemcomitans, intrafamilial transmission of A. actinomycetemcomitans.

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CORRESPONDENCIA AUTOR
María José Contreras Rebollo.
cotecontreras@vtr.net

Trabajo recibido el 04/08/2009.
Aprobado para su publicación el 04/08/2009.

Copyright © 2009.
Sociedad de Periodoncia de Chile, Sociedad de Implantología Oral de Chile y Sociedad de Prótesis y Rehabilitación Oral de Chile.